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Search Results for " liver metastasis "

12

Compounds

Cat No. Product Name Synonyms Targets
T6347 Ki16198 LPA Receptor , LPL Receptor
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activ...
T12580 PTUPB COX , Epoxide Hydrolase
PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively).
T15367 Gadoxetate Disodium Gd-EOB-DTPA Disodium,ZK 139834 Others
Gadoxetate Disodium is used to evaluate focal liver lesions, such as hepatocellular carcinoma or liver metastasis on T1-weighted imaging. It is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary sy...
T10904 CWP232228 Wnt/beta-catenin
CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting t...
T9398 NSC 73150 NSC 97967 Others
6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one (NSC 73150) is a pyrimidine derivative with antitumor activity. Preclinical studies have shown that it inhibits the growth of a...
T77743 TT-012 Others
TT-012 has anti-tumor activity, selectively binds dynamic MITF and disrupts the dimer formation and DNA binding of the latter. TT-012 can inhibit the transcription of MITF in B16F10 melanoma cells. TT-012 inhibited the g...
T3403 Glabridin Q-100692,KB-289522,LS-176045 Reactive Oxygen Species , Tyrosinase , GABA Receptor , Antibacterial , PPAR
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on...
T75089 Selachyl alcohol
Selachyl alcohol, an alkylglycerol compound found in shark liver oil, exhibits properties as an orally active antihypertensive agent with similar activities to antihypertensive neutral renomedullary lipid (ANRL). It is k...
TN5901 Cudratricusxanthone A
Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to in...
T35587 Ganglioside GD1a mixture (sodium salt) Ganglioside B1
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. [1] It can be shed from the surface of tumor cells into the microenvironment where it i...
T79452 Tubulin/HDAC-IN-2
Tubulin/HDAC-IN-2 (Compound II-19k) is a dual inhibitor targeting Tubulin and HDAC, exhibiting IC50 values of 0.403 μM for HDAC1, 0.591 μM for HDAC2, 3.552 μM for HDAC3, and 0.459 μM for HDAC6. The compound induces G2 ph...
T35624 Ajoene
Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =...
TargetMol